The Maudsley Family Study of Psychosis: A Quest for Intermediate Phenotypes by Colm McDonald 0000-00-00 00:00:00

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by Colm McDonald
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The Maudsley Family Study of Psychosis: A Quest for Intermediate Phenotypes by Colm McDonald
Author
Colm McDonald
Publisher
Routledge
Date of release
Pages
218
ISBN
9781841697345
Binding
Hardcover
Illustrations
Format
PDF, EPUB, MOBI, TXT, DOC
Rating
3
25
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Book review

Psychotic disorders such as schizophrenia and bipolar disorder are known to be highly heritable. Despite decades of research, however, the genetic variations conferring susceptibility to these illnesses have yet to be identified. Such genetic variations most likely produce abnormalities of brain structure and function from which the clinical features of psychosis emerge.


The Maudsley Family Study of Psychosis investigates the genetically produced markers of abnormal brain structure and function (‘intermediate phenotypes’) which underlie the clinical syndrome of schizophrenia, and more recently bipolar disorder. In this book, key findings of this important research program, and their implications for this field, are discussed in detail. Contributors outline research examining brain structure and functioning in patients with schizophrenia and their unaffected first degree relatives, incorporating detailed clinical assessments, magnetic resonance imaging, electrophysiology, eye tracking measures and neuropsychology.


This book provides an improved understanding of illness pathways and potential scope for intervention in order to better manage and prevent psychotic disorders and will be of interest to academics and clinicians in the field.

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